Evidence that luteinising hormone receptor polymorphisms may contribute to male undermasculinisation
نویسندگان
چکیده
منابع مشابه
Y chromosome polymorphisms may contribute to an increased risk of male-induced unexplained recurrent miscarriage
The present study aims to explore the relationship between the Y chromosome polymorphisms (1qh+, inv(9), 9qh+, 16qh+, group D/G, Yqh- and Yqh+) and the risk of unexplained recurrent miscarriage (URM). A total of 507 couples with URM were recruited as case group and 465 healthy couples as control group. The Y chromosome polymorphisms of the male individuals were analysed with the G-banding techn...
متن کاملGenetic evidence to exclude the androgen receptor-polyglutamine associated coactivator, ARA-24, as a cause of male undermasculinisation.
Defects in the development and function of the male reproductive system are common (1). Abnormalities range from completely female external genitalia to isolated hypospadias or infertility (1). The underlying basis of the abnormalities is mostly attributable to a reduction in androgen (testosterone or 5-a-dihydrotestoterone (DHT)) action, referred to as undermasculinisation. In some cases of un...
متن کاملPituitary-gonadal axis in male undermasculinisation.
AIMS To study the value of assessing serum concentrations of luteinising hormone (LH), follicle stimulating hormone (FSH), testosterone, and dihydrotestosterone (DHT) in patients with male undermasculinisation not caused by androgen insensitivity. METHODS A retrospective study of a register of cases of male undermasculinisation (20 with abnormal testes, eight with 5alpha-reductase deficiency,...
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Introduction: The etiology of male breast cancer is unclear, but hormonal levels may play a role in development of this disease. It seems that the risk of male breast cancer related to increased lifelong exposure to estrogen or reduced androgen. The aim of this study was to investigate the expression of the steroid hormone receptors including estrogen receptor (ER) and progesterone receptor (PR...
متن کاملLuteinising hormone releasing hormone for incomplete descent of the testis.
Forty boys with 54 incompletely descended testes took part in a double blind, controlled trial of intranasal luteinising hormone releasing hormone. In the control (placebo) group of 18 boys there was no significant change in testicular descent and all required orchidopexy; in the 22 treated boys, however, 12 of 29 testes (42%) were found in a lower position. This study supports the idea that a ...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 2002
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1470103